For large game, the most popular replaceable blade knife is the Havalon Bolt.
It has a thick 60a blade, large and strong enough to for such jobs as popping ball joints and caping around antler bases. The bolt has a very wide user base and excellent reviews. Just watch out when replacing the blade – do it with a tweezers or something like that, don’t use your bare hands. It’s frikkin sharp…
The cheapest place to buy this knife is at amazon. They sell it for 36$ including 10 blades if I remember correctly.
Keep me updated if you can, I would love to hear what you purchased and how you find the knife.